Alternatives to Trifexis for Dogs

We have reviewed the best alternatives to Trifexis for dogs. If you are in a hurry, the table below gives a quick snapshot of the top ones.

Top Choice
Frontline Plus Flea and Tick Treatment...
Second Choice
K9 Advantix II Flea and Tick Prevention...
Best Value
Capstar Fast-Acting Oral Flea Treatment...
What's good?
Waterproof flea and tick treatment. breaks the flea lifecycle, kills the larvae. Contains fipronil and (S)-methoprene, Gives 30 day protection
Works through contact, so fleas, ticks and mosquitoes do not have to bite your dog to die, easy to apply, gives 30 day protection
Tablet based treatment. Kills fleas in 30 minutes
What could be better?
Not much
Some dogs may get rashes and sores, so check the allergic information carefully
Does not offer a consistent solution, as you have to keep giving the tablet to keep fleas away
Prime
-
Top Choice
Frontline Plus Flea and Tick Treatment...
Alternatives to Trifexis for Dogs
What's good?
Waterproof flea and tick treatment. breaks the flea lifecycle, kills the larvae. Contains fipronil and (S)-methoprene, Gives 30 day protection
What could be better?
Not much
Prime
-
Second Choice
K9 Advantix II Flea and Tick Prevention...
Alternatives to Trifexis for Dogs
What's good?
Works through contact, so fleas, ticks and mosquitoes do not have to bite your dog to die, easy to apply, gives 30 day protection
What could be better?
Some dogs may get rashes and sores, so check the allergic information carefully
Prime
Best Value
Capstar Fast-Acting Oral Flea Treatment...
Alternatives to Trifexis for Dogs
What's good?
Tablet based treatment. Kills fleas in 30 minutes
What could be better?
Does not offer a consistent solution, as you have to keep giving the tablet to keep fleas away
Prime

Last update on 2021-05-12 / Affiliate links / Images from Amazon Product Advertising API

Pet dogs often get affected by different types of worms on their skin. These worms should not be taken so lightly as they can cause several health issues and contribute to the decline of your pet dog’s good health. Are you looking for an effective medicine that will protect your furry friend from harmful worms? 

 

Alternatives to Trifexis for Dogs

 

Trifexis is one of the most prominent tablets that can be given to your dog every month for worm-protection. Sometimes, Trifexis may not be suitable for all dogs as different dogs go through individual health conditions and require medications accordingly. 

So, besides Trifexis, you will find several alternative medicines in the market to safeguard your dog from the dangerous effects of worms. However, not all of the alternative medicines to Trifexis are reliable enough.

Therefore, we have selected a handful of medicines that will work as great alternatives to Trifexis for dogs.

Our Top Choice – Frontline Plus Flea and Tick Treatment for Dogs 

The Frontline Plus Flea and Tick Treatment...  is our top choice because:

  • It consists of three effective doses.
  • It offers extreme protection against fleas and ticks.
  • It can easily break the fleas’ life cycle.
  • It is meant for smaller dogs in the range of five to 22 pounds

Alternatives to Trifexis for Dogs

#1 Frontline Plus Flea and Tick Treatment for Dogs 

Frontline Plus Flea and Tick Treatment for Dogs 

Find out more on Amazon

The flea and tick treatment offered by Frontline is specially made for small dogs who weigh approximately 5 to 22 pounds. This treatment pack consists of 3 monthly doses, and after using this product once a month, you can be relaxed about the safety of your dog from ticks and fleas for 30 complete days.

Features and Benefits

  • Quick And Long Lasting Effects On Small Dogs – If the bodyweight of your small dog is around 5 to 22 lbs, then this waterproof ticks and flea treatment can suit it like no other medicine. This waterproof medication offers a quick yet long-lasting effect in treating such worms.
  • Destroys The Life Cycle Of Fleas: Besides effectively reducing the present infestations by killing the adult fleas, the Frontline medicine also destroys the eggs and larvae to control the new infestations. Therefore, it breaks the life cycle of fleas with its effective dose.
  • Complete Protection From Harmful Worms – This versatile medicine not only kills fleas and ticks but also ruins lice and flea eggs for complete protection. The harmful ticks transmitting Lyme disease are also killed by this medicine.
  • Effective And Trusted By Veterinarians – For more than 20 years, veterinarians have been recommending Frontline as one of the trusted medicines for ticks and fleas. The medicine is made of the two most effective components, including methoprene and fipronil. The first one is used to terminate the larvae and eggs of fleas and ticks, whereas the second element kills the adult fleas and ticks. Therefore, you can rely on this medicine for tick and flea control of your eight weeks old puppies or more.
  • 30 Days Complete Protection – The long-lasting formula of Frontline stays in the oil glands of your dog’s skin and provides non-stop tick and flea control for a span of 30 days.

Frontline Plus Flea and Tick Treatment for Dogs

Why should you buy it?

Frontline is a reputed brand of pet medicines that have been on the priority list of veterinarians for almost two decades. The medicine is waterproof, long-lasting, and made of proven components like methoprene and fipronil to offer overall safety from ticks and fleas. By killing flea eggs, larvae, and adult fleas, the medicine successfully destroys the life cycle of fleas on your pet’s skin.

One pack lasts up to 3 months, and one monthly dose is enough to give 30 days of complete protection to your dog. No matter to which age range your dog belongs, if its weight is within 5 to 22 lbs, you should try out this medicine by Frontline to offer tick and flea protection to your furry friend. This product is certainly the best on our list of alternatives to Trifexis for dogs

Frontline Plus Flea and Tick Treatment...
  • Waterproof flea and tick treatment for dogs: Frontline Plus for Dogs provides waterproof, fast-acting, long-lasting flea and tick treatment and control for your dog. This product is approved for use on dogs 5-22 lbs.
  • Break the flea life cycle with frontline: Frontline flea and tick treatment for dogs kills adult fleas plus flea eggs and larvae to stop existing infestations and prevent establishment of new infestations.
  • Kills fleas and ticks: Frontline flea and tick treatment for dogs kills fleas, flea eggs, lice, and ticks. This flea and tick treatment kills ticks, including those that may transmit Lyme disease.
  • Trusted flea and tick protection for dogs: Frontline has been trusted by veterinarians for nearly 20 years. Made with 2 tough killing ingredients, fipronil and (S)-methoprene – one to kill adult fleas and ticks and the second to kill flea eggs and larvae – this fast-acting, long-lasting protection provides flea and tick control for dogs and puppies 8 weeks and older
  • Lasting flea and tick protection: Frontline's long-lasting formula isstored in the oil glands of the pet’s skin to give non-stop flea and tick protection for a full 30 days. Frontline flea and tick treatment for dogs works non-stop for a full 30 days. A 3-dose supply lasts for 3 months.

Last update on 2021-05-12 / Affiliate links / Images from Amazon Product Advertising API

 

You might like to read: Best Dog Food For Elderly Dogs

 

#2 K9 Advantix II for Large Dogs

K9 Advantix II for Large Dogs

Find out more on Amazon

This medicine by K9 Advantix II for tick and flea prevention is created for senior gods whose weight varies between 21 to 55 pounds. One pack of medicine contains six-monthly doses for the healthy and worm-free skin of your dog. The flea and tick-killing formula of this medicine is specifically produced for large-sized dos and does not suit other furry animals like cats.

Features and Benefits

  • Absolute Protection From Worm Bites – The working procedure of K9 Advantix II Flea and tick control medicine is through coming in contact with the worm. So, after applying the cream, worms such as mosquito, lice, flea, and ticks will not bite your dog as they will die after doing so.
  • Faster Results – The easy-to-use tropical formula of K9 Advantix II Flea and tick control works faster and gives great results in a short span.
  • Quick Yet Long-lasting Outcome – As soon as you apply the formula, it will start killing the fleas within the next 12 hours. The impact of the medicine will last till the upcoming 30 days.
  • Apt For Long-Term Usage – The medicine is suitable for year-round fleas and tick control treatment for your big-sized dogs. 

K9 Advantix II for Large Dogs

Why should you buy it?

The fleas and tick control treatment by K9 Advantix II has six doses that are applied on a monthly basis for large dogs of 21 to 55 pounds. The formula is effective and convenient to use for killing ticks, fleas, mosquitoes, and lice appropriately. The effect of this formula is so quick that it starts functioning within 12 hours of its application.

One monthly dose can offer safety to your dog for 30 days. If you are looking for a year-round medication to control fleas and tick on your large dog’s body, then K9 Advantix II will not cause disappointment. This is our second choice in our list of alternatives to Trifexis for dogs.

K9 Advantix II Flea and Tick Prevention...
  • 6 monthly applications of K9 Advantix II flea and tick prevention for large dogs weighing 21-55 pounds
  • K9 Advantix II flea and tick prevention for dogs works through contact, so fleas, ticks and mosquitoes do not have to bite your dog to die
  • K9 Advantix II flea and tick control for dogs is an easy to apply topical formula
  • Starts working to kill fleas within 12 hours and keeps working for 30 days
  • Suitable for effective year-round dog flea and tick treatment for large dogs

Last update on 2021-05-12 / Affiliate links / Images from Amazon Product Advertising API

#3 Seresto Flea and Tick Collar for Dogs

Seresto Flea and Tick Collar for Dogs

Find out more on Amazon

Seresto Flea and Tick Collar suits dogs in all life stages, starting from 7 weeks puppies to older dogs of 18 pounds( 8 kg) or above. After its initial application, your dog will remain protected from the bite of lice, fleas, and ticks for the next eight months. Veterinarians especially suggest this medication because of its functional and convenient formula.

Features and Benefits

  • No Need For Monthly Doses – This formula does not require monthly treatments. One dose can give your dog safe from ticks and fleas for eight months.
  • Protection From The Fleas’ Contact – Fleas and ticks will not come in contact with your dog after the medicine’s application as they will be killed if they do so.
  • See The Effect Within 24 Hours – The effect of the formula begins within 24 hours of its first application.
  • Effective In Killing Sarcoptic Mange & Lice – This tick and fleas collar for big-sized dogs can even help to handle sarcoptic mange and destroy lice at the same time.
  • Non-Greasy, Odorless & Convenient – Veterinarians usually advise dog owners to use this medicine because of its odorless, non-greasy, and easy to apply formula.

Seresto Flea and Tick Collar for Dogs

Why should you buy it?

If you are trying to provide a conveniently applicable protection formula for tick and fleas treatment, then Seresto Flea and Tick Collar can keep our dogs safe for eight months. Within 24 hours of applying the formula, you will observe its effect on your dog’s skin to kill lice, fleas, and ticks. This collar does not need monthly doses. Also, the ointment is non-greasy and odorless, which makes it convenient for use on a dog’s skin. Even veterinarians suggest this brand, so you do not have to worry about its quality and reliability.

Seresto Flea and Tick Collar for Dogs,...
  • Provides 8-months of continuous flea and tick prevention
  • Seresto flea and tick collar for large dogs works through contact, so fleas and ticks do not have to bite your dog to die
  • Veterinarian-recommended flea and tick prevention for dogs in a convenient, odorless and non-greasy collar; No need for messy monthly treatments
  • Starts to repel and kill fleas within 24 hours of initial application
  • Flea and tick collar for large dogs also helps treat and control sarcoptic mange and kills lice

Last update on 2021-05-12 / Affiliate links / Images from Amazon Product Advertising API

 

You might like to read: Best Dog Food For Elderly Dogs

 

#4 Capstar Fast-Acting Oral Flea Treatment for Large Dogs

Capstar Fast-Acting Oral Flea Treatment for Large Dogs

Find out more on Amazon

Large dogs between the weight of 26 to 125 lbs are particularly suitable for this oral treatment, but Capstar helps to manage issues like lice, fleas, and ticks. There are six monthly doses in one pack. Even there is no need to consult a veterinarian to offer this treatment to your pet dog. The oral treatment is also effective on cats.

Features and Benefits

  • See The Results Within 30 Minutes – It is one of the fastest oral treatments to kill ticks and fleas. You will start noticing its effect within 30 minutes of its intake.
  • Fast Recovery From Fleas – Due to its high strength in treating re-infestation, it removes fleas from your dog’s skin at a faster speed. Even if the fleas come back to your dog’s body, you can offer it another dose as frequently as once a day.
  • Fleas Falling Off The Dog’s Skin – Fleas will fall off your dog’s skin after chewing the tablet due to its fast flea infestation tackling power.
  • No Requirement For Veterinarian’s Prescription – It is not necessary to have a veterinarian prescription to purchase Capstar oral treatment. You can buy it as OTC medicine to kill fleas and ticks orally.
  • Suitable For Large Dogs – The oral flea tablets by Capstar can be used safely for puppies and dogs with an approximate bodyweight between 25.1 to 125 lbs. You can apply it on the skin of four weeks or older pets.

Capstar Fast-Acting Oral Flea Treatment for Large Dogs

Why should you buy it?

Unlike other flea ointments, Capstar offers an oral tablet that is easy to use. There is no worry about greasy and smelly ointment while using this oral flea tablet. You will not require to consult a veterinarian before using this affordable oral medication. The instant reaction of this oral tablet can be seen within 30 minutes of its intake. You are guaranteed to see fleas falling off the pet’s skin after taking the dose of the tablet.

Sale
Capstar Fast-Acting Oral Flea Treatment...
  • FAST-ACTING FLEA TREATMENT: One oral flea tablet starts killing fleas within 30 minutes.
  • TACKLE FLEA INFESTATIONS FAST: Give Capstar oral flea treatment and watch dead fleas fall off your pet.
  • TREAT RE-INFESTATIONS FAST: If your pet gets re-invested with fleas, simply give another dose as often as once a day.
  • WITHOUT A VET PRESCRIPTION: Flea treatment without needing a veterinarian prescription, administer this cat flea tablet orally to kill adult fleas fast.
  • KILL ADULT FLEAS: Capstar oral flea treatment tablets (57 mg) are safe for dogs and puppies from 25.1-125 lbs., four (4) weeks and older.

Last update on 2021-05-12 / Affiliate links / Images from Amazon Product Advertising API

#5 Advantus (Imidacloprid) 7-Count Flea Chews for Small Dogs

Advantus (Imidacloprid) 7-Count Flea Chews for Small Dogs

Find out more on Amazon

One pack of Advantus contains seven soft flea chews which are used to treat fleas, ticks, and lice in a small dog’s body with an average body weight between 4 to 22 pounds. Dogs or puppies that are aged ten weeks or more can chew these tablets without even a doctor’s prescription.

Features and Benefits

  • Kill The Fleas With A Single Dose – The pack of flea chews containing seven soft chews can kill adult fleas with a single dose of medicine. No harm will be caused if you give the chew to your dog on a frequency of once every day.
  • Appropriate For 10 Weeks Or Older Dogs – 10 weeks or older puppies and dogs are suitable to chew these tablets for fighting fleas and ticks.
  • Rapid Destruction Of Fleas – Within 1 hour of taking the Advantus flea chews, your dog will start to get rid of fleas and ticks on its skin.
  • Particularly Made For Small Dogs – The chews are soft and approved especially for serving their purpose to small dogs.
  • No Need For Veterinarians’ Consultation – There is no requirement for taking a veterinarian’s prescription for buying the Advantus soft chews for your dogs. 

Advantus (Imidacloprid) 7-Count Flea Chews for Small Dogs

Why should you buy it?

If you are looking for the perfect flea treatment for your little puppy or small dogs, then these soft flea chews Advantus should be on the top of your priority list. You do not need to get a prescription from your veterinarians to buy or use this medicine. These chews can be purchased as an emergency medicine to see instant results for fleas and tick treatment because it begins to kill fleas within one 1 hour of its intake. Even the daily dose of this medicine does not create any health issues for dogs.

Advantus (Imidacloprid) 7-Count Flea...
  • Contains 7 small dog flea soft chews: A single dose of Advantus kills adult fleas on a dog. It is safe to repeat treatments as needed, up to once per day
  • Chewable flea treatment for dogs and puppies age 10 weeks and older
  • Advantus flea chews for small dogs start killing fleas within 1 hour
  • Advantus flea chews for small dogs are a convenient, savory soft chew that is approved
  • Available without a prescription

Last update on 2021-05-12 / Affiliate links / Images from Amazon Product Advertising API

 

You might like to read: How to Tell if Your Dog is Going Blind

 

#6 Amazon Brand – Solimo Flea and Tick Remover

Amazon Brand - Solimo Flea and Tick Topical Treatment for Dogs

Find out more on Amazon

Solimo’s product helps remove flea eggs, flea larvae, fleas, and ticks. The products acts quickly and give a lasting benefit to your dog.It is even effective against Lyme disease.

Features and Benefits

  • Fast-acting: It removes ticks and fleas in just 24 hours. It has two ingredients that remove fleas by eliminating their eggs and larvae.
  • Long-lasting: Your dog will remain free from ticks and fleas for upto a month after applying this product once.
  • Waterproof: The product keeps your dog safe from water for upto 24 hours after application.
  • Ingredients used: It contains (s)-methoprene, and fipronil

Amazon Brand - Solimo Flea and Tick Topical Treatment for Dogs

Why should you buy it?

If you are looking for a long-lasting and fast-acting product that comes in a reasonable price range, Solimo’s flea and tick remover is a very good bet.

Sale
Amazon Brand - Solimo Flea and Tick...
  • Includes three 0.045 fluid ounce tubes of Solimo Topical Flea and Tick Treatment for Medium Dogs (23-44 pounds)
  • Solimo topical flea and tick prevention for dogs kills fleas, flea eggs, flea larvae, ticks, and chewing lice for up to 30 days after application
  • Contains fipronil, and (s)-methoprene, the same active ingredients used in Frontline Plus
  • For best results, apply directly to dry skin on your dog's back-between the shoulder blades-on a monthly basis and treat your home and yard at the same time
  • A fast-acting, long lasting topical flea treatment for dogs that stops the flea life cycle and kills flea eggs and larvae for up to 4 weeks

Last update on 2021-05-12 / Affiliate links / Images from Amazon Product Advertising API

Conclusion: Alternatives to Trifexis for Dogs

Trifexis is definitely very effective in protecting your dogs against any kind of heartworm disease and even prevents your dogs from getting infected by fleas. The above-mentioned alternatives for Trifexis are equally effective and protect your dog against any kind of flea infestations or any infections spread by insects.

Using these protective dog collars is extremely beneficial for a healthy and active pet dog. Let us hope that this article can help you in finding the best alternatives to Trifexis for dogs. 

In our opinion, the Frontline Plus Flea and Tick Treatment...  is the best among the various alternatives to Trifexis for dogs that we have considered because it can have a long-lasting effect on the fleas and ticks for your dogs. 

 

Alternatives to Trifexis for Dogs

 

The K9 Advantix II Flea and Tick Prevention...  is our next best choice in our list of alternatives to Trifexis for dogs because it can get faster results. 

If you are looking for a value for money option, you can also consider the Capstar Fast-Acting Oral Flea Treatment... , which offers great value and features at a very reasonable price point. 

Other articles of interest:

References:

[1] Field evaluation of the efficacy and safety of a combination of spinosad and milbemycin oxime in the treatment and prevention of naturally acquired flea infestations and treatment of intestinal nematode infections in dogs in Europe – PubMed (nih.gov)

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